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MannKind’s patient-focused oral inhalation drug delivery technologies include a dry powder formulation capability coupled with an innovative, elegant, breath-powered delivery device. We are applying these technologies to facilitate partnered drug development programs for proprietary compounds.

MannKind has numerous collaborations across therapeutic areas that demonstrate the efficacy and safety of the technologies. Patients self-administer these dry powder formulations with small, easy-to-use, breath-powered inhalers. Following inhalation, drugs are absorbed very rapidly, essentially mimicking intra-arterial administration. MannKind has evaluated this versatile pulmonary drug delivery platform across multiple therapeutic areas, including diabetes, metabolism, respiratory disease, osteoporosis and pain.

For companies interested in exploring the feasibility of a Technosphere formulation using their own active pharmaceutical ingredient (API), MannKind offers a feasibility evaluation. These evaluations involve preparation and characterization of API/Technosphere formulations. These powders are tested for performance in MannKind’s inhalers. Additionally, MannKind works with the partner to test these powders in relevant nonclinical PK/PD models. These studies can often been completed within 6 months. 

MannKind seeks to establish partnerships to build therapeutic programs of significant clinical and commercial value. Whether through strategic alliances, licensing arrangements and/or research collaborations, MannKind's partnering approach is based on a flexible, creative methodology designed to establish mutually beneficial relationships that are positioned to capture upside potential beyond what either partner could achieve individually.

Relay brings you BD Live! – a software solution providing business intelligence to life science professionals to validate opportunities, discover new assets, and assess their pipelines against their competitors. BD Live! provides real-time trend monitoring and comparative asset analysis and complements existing evaluation models to help business development professionals hone in on promising new technologies and avoid transactions that have limited potential.

Vice President, Licensing and M&A

AriVan Research LLC (AVR) is a specialized consulting firm that works closely with biopharmaceutical companies, diagnostic companies, medical device manufacturers, and other clients to support business development, commercialization and R&D activities.  Our expertise involves conducting in-depth primary research with KOLs, clinical investigators, healthcare company personnel, payers, and other industry sources to address important business- and scientific-related questions and issues.  A thorough analysis of secondary and/or audit data is often completed as well.  From there, our highly-experienced group of MBAs, MDs & PharmDs analyzes the information to provide rational and insightful recommendations.  

Ritter Pharmaceuticals, Inc. is a specialty pharmaceutical company developing therapeutics based upon colonic adaptation to treat gastrointestinal diseases with an initial focus on lactose intolerance. Colonic adaptation improves colon function by selectively increasing the growth of beneficial bacteria in the colonic ecosystem (digestive tract).

Ritter Pharmaceuticals, Inc. is rapidly establishing itself as the world’s leader in lactose intolerance research based upon its scientific team and their cutting edge research in this field. RP-G28, Ritter's lead product, has been studied in a Phase 2 trial and is a first-in-class compound. RP-G28 has the potential to become the first FDA-approved drug for the treatment of lactose intolerance, a debilitating disease which affects over 1 billion people worldwide.

JRX Biotech is focused on (1) pain management and (2) dermatology applications.  We are a post revenue specialty biochemistry technology company.

We develop topical products using our patented delivery system platform (formfactors: liquid solutions, serums, lotions, creams, sprays).

DermX Megasphere Delivery System -- a dermal/transdermal delivery system technology platform that has been independently proven to allow high payloads of large molecular weight molecules to passively penetrate into and through human skin.

DermX Features / Benefits:

  --Passive, topical solution

  --Patented

  --Proven (Franz Cell and in vivo)

  --High payloads delivered (>20% of the applied dose penetrating)

  --Large molecules delivered (>11kD)

  --No irritation

We are looking to:

  (1) Co-develop our lead topical pain relief patented product (first-in-class).

  (2) Co-develop our pipeline of patented topical pain relief products.

  (3) Out-license our platform delivery system technology.